医疗专业人员

下面列出了当前开展的临床试验。

根据地点、状态和其他条件对此研究列表进行过滤。

1. Study to Validate the Use of a Lymphatic Imaging Protocol to Stage Disease Severity in Patients with Lymphedema

   Jacksonville, Fla.

   The purpose of this study is to validate the use of a lymphatic imaging protocol to stage disease severity in patients with lymphedema and serve as a biomarker for microsurgical treatment response.

2. A Study of the Ability to Predict Lymphedema Development Following Axillary Surgery for Breast Cancer and Its Effects on Patient Survivorship

   Jacksonville, Fla.

   The purpose of this study is to better understand the anatomy of the lymphatic structure and the molecular process that leads to the over production of lymph fluid.  This proposal will begin intense lymphedema screening and identify baseline characteristics potentially predisposing someone to lymphedema, and identify molecular markers that might be altered to prevent lymphedema. 

3. A Study of Endovascular Biopsy and Endothelial Cell Gene Analysis in Endovascular Procedures

   Rochester, Minn.

   The purpose of this study is to determine endothelial gene expression from guidewire biopsy during clinically indicated endovascular procedures. The genetic analysis will be measured against clinical outcomes and treatment response (response to non-coated and drug-coated technologies and different embolic agents depending on the procedure).

4. A Study to Evaluate Progenitor Cells for Patients with Degenerative Lung Disease

   Rochester, Minn.

   The purpose of this study is to use a patient's own cells to fabricate a recellularized scaffold to repopulate the lung and restore function that could offer a solution for patients with degenerative lung disease.

5. A Study to Evaluate Maternal-fetal Immune Responses to Fetal Surgery

   Rochester, Minn.

   The purposes of this study are to determine whether maternal T cells are activated and expand after in utero intervention, and to determine whether placental macrophages and histology in the maternal-fetal interface exhibit increased activation and inflammation in surgical cases born preterm (<37 weeks) compared to term.

6. Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to evaluate the continued safety and probable benefit of the MID-C system for 5 years post-implantation in Adolescent Idiopathic Scoliosis (AIS).

7. MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma (MelMarT)

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to determine differences in the rate of local recurrence and melanoma specific survival. A reduction in margins is expected to improve quality of life to back up evidence that less radical margins of excision may be just as safe.  

8. A Study to Collect Ovarian Tissue from Girls Undergoing Fertility-preserving Cryopreservation

   Rochester, Minn.

   The purpose of this study is to study the handling of ovarian tissue, cryopreservation technology, and oocyte maturation for female pediatric cancer patients and other female patients whose future fertility will be affected due to a disease or treatment.

9. A Quality of Life Assessment of Patients with Biliary Obstruction Undergoing Endoscopic or Percutaneous Drainage

   Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla.

   The aim of this study is to compare the quality of life of patients with biliary obstruction who have undergone an endoscopic or percutaneous drainage. The quality of life of patients witll be assessed using the validated "European Quality of Life-5 Dimensions Questionnaire" and the "Intervention-Dependent Questionnaire" which was developed according to current literature as well as the expert opinion of gastroeneterologists.

    

10. A Study to Explore the Mechanisms that Separate Responders Versus Non-responders to Treatment such as Immunotherapy, Target Therapy and Chemotherapy in Lung Cancer Patients

    Jacksonville, Fla.

    The purpose of this study is to explore the underlying mechanisms that distinguishes responder versus non-responders to treatment such as immunotherapy, target therapy and chemotherapy in lung cancer and mechanisms of resistance. The information generated from this study will likely help to design the optimal strategies to improve clinical outcomes in lung cancers.