Clinical trials Below are current clinical trials.5 studies in Early-Onset Colorectal Cancer Group (open studies only). Filter this list of studies by location, status and more. Gastrointestinal-Related Cancers and Diseases Rochester, Minn. The purpose of applying to the Institutional Review Board (IRB) for the collection of GI-related tissue is to enable comprehensive molecular investigations into the mechanisms underlying gastrointestinal cancers and diseases. A Colon Bank for Early Detection of Colon Cancer Rochester, Minn. The purpose of this study is to establish a biobank of samples (blood and stool) to support the development of non-invasive tests for early detection of colon cancer and its precursors. Evaluate REC-4881 in Patients With FAP (TUPELO) Rochester, Minn., Scottsdale/Phoenix, Ariz. The purpose of this trial is to designed to characterize the safety, tolerability, PK, PD, and preliminary activity of REC-4881 administered orally (PO) at multiple doses on a once daily schedule in participants with phenotypic classical FAP with disease involvement of the duodenum or the residual colon/rectum/pouch as the primary disease site. Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome Rochester, Minn., Scottsdale/Phoenix, Ariz. The purpose of this study is to evaluate if the combination of trivalent adenovirus-5 (Tri-Ad5) vaccines and IL-15 superagonist N-803 reduces the incidence of colorectal neoplasms in patients with Lynch syndrome (LS). Gemini Study to Evaluate the Integration of Cancer Genetic Testing into a Cancer Clinical Practice at Mayo Clinic at Arizona Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to determine the prevalence of genetic mutations in cancer patients from various ethnic populations seeking care at Mayo Clinic cancer clinics. Request an appointment ResearchCosts & insurance June 17, 2025 Share on: FacebookTwitter Early-Onset Colorectal Cancer GroupSectionsOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsResearchClinical trialsCosts & insuranceReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsResearchClinical trialsCosts & insuranceReferrals ORG-20584173 Medical Departments & Centers Early-Onset Colorectal Cancer Group